Fixed drug eruptions caused by cross-reactive quinolones

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Fixed drug eruptions caused by cross-reactive quinolones

Fixed drug eruptions (FDE) are the common dermatological adverse drug reaction accounts for 16-21% of all cutaneous drug reactions in India. Drugs most frequently implicated in FDE are antimicrobials, anticonvulsants, and nonsteroidal antiinflammatory drugs. Here, we report a rare case of bullous FDE due to ciprofloxacin followed by ofloxacin administration.

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Fixed drug eruptions induced by cross-reactive imidazoles.

Adverse drug reactions are a frequent cause of consultation in allergology and dermatology services that affect up to 10% of the population (20% in hospitalised patients). More than 10% of them are hypersensitivity reactions. Fixed drug eruptions (FDE) are defined as erythematous plaques recurring at the same anatomical localisation in every occasion that the drug is re-administered to the alle...

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Genital fixed drug eruptions.

Twenty nine patients with genital fixed drug eruptions were studied during one year. In 15 the genitalia were exclusively affected, whereas the other 14 had cutaneous lesions in addition. It was striking that those whose lesions were exclusively genital reported for consultation much earlier. Drug history was the mainstay of diagnosis. Provocation tests with graded doses of the suspected drug(s...

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Cetirizine induced bullous fixed drug eruptions

Background Hand and/or feet eczema may be due to contact dermatitis, either irritant or allergic in nature. Difficulties often arise in distinguishing purely endogenous eczema from the possibility of contact dermatitis clinically. Patch test is carried out to detect the presence of allergic contact dermatitis. This is important for optimum patient care and to obtain a favourable outcome. Object...

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Study of fixed drug eruptions in Karachi.

Thirty three patients with fixed drug eruptions were subjected to provocation tests. Otrimoxazole was the commonest drug responsible, followed by trirnethoprim, Beserol and tinidazole. There was cross sensitivity among sulphonamides. Polys&isitivity was recorded with one case each of Ampicillin and Beserol to Cotrimoxazole (JPMA 37: 1 75, 1987).

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ژورنال

عنوان ژورنال: Journal of Basic and Clinical Pharmacy

سال: 2014

ISSN: 0976-0105

DOI: 10.4103/0976-0105.134986